Dr. Adrián Gómez-Suárez
Organic Chemistry
Research
The Gómez-Suárez group focusses on the development of novel and effective synthetic methodologies to access interesting structural motifs for chemical and biological processes.
Radical deoxyfunctionalisations:
Alcohols are among the most prominent functional groups in organic molecules. As such, they can be used as handles to introduce further functionality via nucleophilic substitution reactions. This approach is inffective when dealing with tertiary or sterically hindered alcohols. Therefore, our goal is to develop straight-forward methodolgies to overcome this issue using radical chemistry.
Synthesis and modification of amino acids:
Amino acids are versatile building blocks for chemical and biological syntheses. Therefore, it is highly interesting to develop efficient technologies for their synthesis and derivatisation. To accomplish this, we use a combination of radical and organometallic chemistry.
Publications
Radical‐Based Synthesis and Modification of Amino Acids,
Troyano F., Merkens K., Anwar K., Gómez‐Suárez A.
Angew.Chem. Int. Ed. 2021, 60,1098–1115
Synthesis of Unnatural alpha-Amino Acid Derivatives via Light-mediated Radical Decarboxylative Processes
Merkens K., Troyano F., Djossou J., Gómez‐Suárez A.
Adv. Synth. Catal. 2020, 362, 2354-2359
Light‐mediated Formal Radical Deoxyfluorination of Tertiary Alcohols via Selective Single Electron Oxidation with TEDA2+·
Troyano F., Ballaschk F., Jaschinski M., Özkaya Y., Gómez‐Suárez A.
Chem. Eur. J. 2019, 25, 14054
